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Investigating the Role of IGF-1 and Insulin Receptor Mutations in the Pathogenesis of Keratosis Pilaris: A Theoretical Framework for Symptomatology and Underlying Mechanisms Author: Devin Beaubien Last Updated: 4/4/2025 Introduction The skin condition Keratosis Pilaris(KP) is primarily the result of a skin barrier issue caused by some skin cells not maturing/forming a cohesive interfollicular lipid barrier