1:1000) to exclude dead cells and were stained with a two-by-two combination of ROS, MITO, and GSH dyes as specified above
This allosteric targeting approach can effectively avoid pseudotargeting or loss of target, and the plug-and-play targeting moieties effectively improved the biocompatibility and stability of the formulation and showed good universality for various lipid-based carriers and membrane receptors
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doi: 10.3389/fphar.2025.1513125 Received 17 October 2024 Accepted 07 March 2025 Published 28 March 2025 Volume 16 - 2025 Edited by Eliot Ohlstein, Drexel University School of Medicine, United States Reviewed by Robertas Badaras, Vilnius University, Lithuania Qiyan Wang, University of Michigan, United States Updates Copyright 2025 Di Fulvio, Rathod and Khader
The mechanisms underlying protective effects of RT on the brain and its role in reducing risk of neurodegeneration are discussed herein