FCCP disrupts ATP production by transporting protons across the mitochondrial inner membrane, collapsing the proton gradient, and allowing the measurement of the maximum OCR, which reflects the electron transport chains capacity and substrate availability
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Activation of fatty acids to highly polar thiol esters, i.e., acyl-CoA, occurs on the outer mitochondrial membrane, but to enable transport across the inner mitochondrial membrane, the acyl group is transferred to carnitine with formation of acylcarnitines, which can enter the mitochondria with the assistance of translocases
Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys
As modern research delves into the connection between our dietary habits, the microorganisms that inhabit our gut, and the expression of rosacea, we find ourselves on the cusp of a paradigm shift in the way we approach skin care and wellness
