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These medications are most effective when combined with lifestyle modifications, including a healthy diet and regular physical activity

Besides berberine, other botanicals including citrus fruit extracts, green tea, saffron, and coffee bean extract have been studied for their potential role in GLP-1 production with mixed results

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GLP-1 , or glucagon-like peptide-1 , is a hormone that plays a vital role in regulating blood sugar levels and insulin response