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Persistent nausea and vomiting that prevents adequate oral intake or leads to dehydration requires medical intervention, as this may indicate gastroparesis or other complications requiring dose adjustment or alternative management strategies

High vitamin B12 levels are often seen as less concerning because they usually dont cause symptoms and are typically the sign of an underlying condition, not a direct health risk 2 , 5

Researchers also suspect that the profound hormonal and metabolic changes triggered by GLP-1 drugs may play a role

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Compared with the class of oral diabetes medications called SGLT2 inhibitors, GLP-1 therapies usually result in greater weight loss and stronger blood sugar lowering

Report any unusual symptoms during antibiotic treatmentpersistent nausea beyond normal semaglutide side effects, severe vomiting, abdominal pain, or signs that your infection isn't improving