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Here's an overview of the kind of weight loss results you might expect: Clinical Trial Averages: In a major trial (SURMOUNT-1) involving over 2,500 adults without diabetes, tirzepatide helped patients lose an average of about 15% of their starting body weight at the mid-range doses, and up to 22.5% of body weight on the highest 15 mg dose over 72 weeks [4]

Rebouche CJ, Mack DL, Edmonson PF