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Areas most commonly affected by excess skin after GLP-1 weight loss: Abdominal Region The stomach area typically shows the most dramatic changes, with loose skin creating an apron effect that hangs over the lower abdomen

Dehydration: Electrolyte imbalance and dehydration can promote muscle spasms

Freckles are small, light-brown spots that appear and darken with sun exposure, and theyre mostly genetic

Additionally, other intestinal hormones like cholecystokinin (CCK) and glucose-dependent insulinotropic polypeptide (GIP) amplify GLP-1 release

doi:10.1186/s12959-016-0119-8 [PubMed] Guoyao Wu

They found that there were 179 reported cases of alopecia associated with tirzepatide, while semaglutide returned 199 cases