For now, the take-home messages for an informed patient or provider are: GLP-1 RAs (Ozempic, Wegovy, Mounjaro, etc.) are highly effective for T2D and obesity, offering glycemic control and substantial weight loss along with protective effects on the heart and possibly kidneys
Additionally, overexpression of thioredoxin (Trx) has been demonstrated to inhibit the progression of insulin resistance in both type 1 and type 2 diabetes in vivo (Yamamoto et al., 2008)
Tregs are responsible for inhibiting immune responses by reducing the severity of chronic inflammation
GHK-Cu can support your own collagen production and gradually soften the look of fine lines, but it is not an instant wrinkle eraser
Kanai M, Imaizumi A, Otsuka Y, Sasaki H, Hashiguchi M, Tsujiko K, et al
The general approach is to restart the titration schedule from the lowest dose (1.5mg), with your prescriber advising on the most appropriate starting point for your circumstances