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In real-world practice, those discontinuation rates may be even higher. Andrade said the medication could be helpful for people with severe obesity, who may still have trouble losing weight on the existing GLP-1 medications, although shed like to see more data on the side effects

FAQ Q1: What is the Advanced Recomp Stack

Body weight reduction of retatrutide surpass the effectiveness of many existing treatments

The tapering protocol: step by step If you and your provider decide that discontinuation is the goal, doing it right dramatically improves your chances of maintaining results

Participants taking the highest 12 mg dose of retatrutide lost an average of 28.3% of their body weight (31.9 kg) over 80 weeks, while those on the lowest 4 mg dose lost an average of 19.0% of their body weight (21.4 kg)

Patients who havent succeeded with behavioral approaches alone