[6] [7] According to the official MHRA/EMC Summary of Product Characteristics, the most frequently reported adverse effects of Wegovy are gastrointestinal in nature , including: Nausea (very common, affecting more than 1 in 10 people) Diarrhoea (very common) Vomiting (common, affecting up to 1 in 10 people) Constipation (common) Abdominal pain (common) Fatigue is also listed as a common side effect in the SmPC
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On the other hand, inhibiting SQOR in chronic heart failure (where H 2 S signaling is low) has been shown to be cardioprotective