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While mild stomach pain can be a common side effect, severe and persistent pain is not normal and requires immediate medical attention

Recent advances have expanded the use of MNs for GLP-1 receptor agonists, which are traditionally limited by poor oral bioavailability and require frequent subcutaneous injections

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Mendelian randomization analysis also showed an inverse relationship between GLP-1 receptor expression and severe DR, indicating the potential of GLP-1RAs in reducing the risk of DR in type 2 diabetes patients (Zheng et al., 2023)

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