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In subjects with normal renal function, coadministration of empagliflozin with probenecid resulted in a 30% decrease in the fraction of empagliflozin excreted in urine without any effect on 24-hour urinary glucose excretion

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3 Riboflavin and neurological disorders In the sections that follow, each disease is introduced through its mechanistic link to riboflavin metabolism, then examined in light of pre-clinical data, clinical experience, and expert-consensus recommendations

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In some cases, untreated vitamin B12 deficiency can lead to behavioral and health issues such as decreased brain function, depression, osteoporosis, and macular degeneration

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