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The FDA's 503A framework also requires bulk substances used by compounders to meet applicable standards and be accompanied by a valid certificate of analysis, with the agency advising compounders to scrutinise their bulk-drug suppliers

J Clin Oncol 19 (5): 1430-6, 2001

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The numbers show a likely decrease in traffic across all segments of the food-away-from-home business, with the impact least detrimental to fine-dining restaurants and the greatest drop-off affecting convenience stores