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Cons: Not everyone responds the same

This suggests LL-37 acts as an alarm system, redirecting mast cells from allergic mode to infection-fighting mode when bacteria are present

However, clinical translation remains limited by key challenges: low colonization efficiency of conventional oral formulations in the complex gastrointestinal milieu

lean proportion of total mass rose

To illustrate, a 2015 study showed that rats fed a collagen peptide absorbed more than 63% of the collagen, whereas other orally administered peptides have exhibited bioavailability rates as low as 1-2%.12 13 BPC-157 is an exception, too it remains stable in gastric juice for more than 24 hours, allowing it time to pass through the gastrointestinal walls15 but its often used in conjunction with the not-so-orally-bioavailable TB4