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GLP-1 medications work by mimicking the effects of the naturally occurring hormone GLP-1, which plays a vital role in appetite regulation and food intake

Inconsistent treatment can cause recurrence or resistance

Study that establishes the efficacy and safety of liraglutide in patients with T2DM and moderate renal impairment, but shows a lack of effect of acute and prolonged therapy with this GLP-1R agonist on eGFR trajectory compared to placebo

A 28-year-old with normal hormones and healthy testes will likely respond very differently than a 45-year-old with low testosterone and metabolic syndrome

European Medicines Agency decision P/0336/2024 Paediatric Investigation Plan for retatrutide