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Lo studio STEP 1 Extension ha seguito pazienti che avevano perso in media il 17% del peso corporeo con semaglutide: a un anno dalla sospensione, senza supporto strutturato, ne avevano recuperato circa il 12%

Conversely, genera such as Erysipelatoclostridium , Bacteroides , and Lachnoclostridium were elevated in the db/db group but notably reduced after treatment, suggesting that Tirzepatide may improve metabolic function by modulating the microbiota (Figures 7BE)

FDA-approved September 2019

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