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It sits in the middle ground that characterizes many endogenous bioactive peptides: genuine biology, genuine effects, and genuine unanswered questions about how far those effects can be pushed therapeutically

Alzheimer disease in 2016: Putting AD treatments and biomarkers to the test

ROS mutate genes involved in various metabolic pathways throughout the body and prevent the detoxification and excretion of toxic waste

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The goal here is not to dismiss these compounds, several of which are genuinely interesting research tools, nor to hype them

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