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Animal studies were performed according to the National Institutes of Health Guide for the Care and Use of Laboratory Animals and approved by the Ethics Committee of the Second Hospital of Shandong University

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Thus, fasting increased mRNA expression in the hypothalamus of rats, and the ICV administration of GLP-1 reduced that effect [135]

In addition to main manifestations of HDP, such as maternal hypertension, proteinuria, and fetal growth restriction (232234), fetal brains also exhibited changes in response to HDP exposure, but their direct relevance to ASD remains unclear

Semaglutide is administered subcutaneously, into the fat layer just beneath the skin

Initial studies have shown promising outcomes in weight reduction and glycemic control in patients with obesity and type 2 diabetes