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Some patients may qualify for one product under one pathway and another product under a different one

Circulation 151 , 14951497 (2025)

Notably, More recent studies suggest that PYY signaling interacts synergistically with GLP-1 and other satiety peptides, raising the possibility that lower-dose combination strategies could harness its anorectic effects while minimizing intolerance (Mentis et al., 2021

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This precision approach maximizes efficacy while minimizing unnecessary dose escalations or side effect exposure