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Although these animal models (such as those employing chronic intermittent ethanol exposure paradigms) provide compelling mechanistic insights, extrapolation to human populations should be approached with caution, given interspecies physiological and behavioral differences

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[3] Maintaining long-term weight loss requires a combination of ongoing lifestyle changes and sticking to your GLP-1 medication

Toujeo typically causes weight gain because insulin promotes glucose uptake into cells, including fat cells, and reduces glucose loss through urine