Changes in GIP secretion could contribute to the loss of incretin effect observed in patients with type 2 diabetes (Holst et al., 2011)
Other pharmacologic targets under research cover a wide range of mechanisms of action including dopamine, GABA, glutamate, opioid, and serotonin pathways (Shen, 2018
doi: 10.1016/j.tifs.2016.06.004 100 ZhangW.ZhangT.JiangB.MuW
Functional Foods: continue to dominate the weight management market, and are expected to grow from around $280.7 to over $586 billion, highlighting a significant transition towards everyday, food-based wellness solutions and reflecting the need for long-term preventive health through nutrition
GSSG disodium
Averaged out, this is roughly **1.4 kg per month** (or about 3.1 lbs per month)