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02) Alcohol Interaction: May enhance the blood sugar-lowering effect of SEMALIX 3 TABLET

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FIGURE 4 3.4 Nitazoxanide reduced apoptosis in rats with MTX-hepatotoxicity MTX significantly induced hepatic apoptosis as demonstrated by increased proapoptotic markers, Bax level, and caspase-3 activity (Figures 5A, D) while reduced antiapoptotic Bcl-2 level (Figure 5B) and increased Bax/Bcl-2 ratio (Figure 5C) compared to CTRL group

4 The Lancet Cagrilintide phase 2 dose-findingLau DCW et al

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