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Andrew Huberman, a neuroscience professor at Stanford, has stated publicly that "BPC-157 is one of the more interesting peptides because of the gastric juice origin and the acid stability, but the lack of human trials is a real limitation that people tend to overlook." This sentiment reflects the tension between preclinical promise and clinical evidence gaps

More recently, a long-acting exendin-4-based analog bound to the Fc portion of immunoglobulin G (IgG) known as efpeglenatide is under clinical development, and would also be suitable for a once-weekly injection [8,9]

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These can be mild reactions or severe reactions, depending on the individual