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Cancer Prevention Research Clinical validation shows suppression of 70% of genes overexpressed in aggressive metastatic colon cancer, reduced tumor incidence, and enhanced immune surveillance capabilities

Lauver DA, Kaissarian NM, Lucchesi BR

Washington, DC: The National Academies Press

These metabolic changes lead to glomerular hyperfiltration, enlargement, and increased proximal tubular glucose reabsorption via sodium-glucose cotransporter 2, resulting in elevated intraglomerular pressure and hyperfiltration [25]

Eckenstaler, R

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