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The two main options have different mechanisms and potential benefits: Semaglutide vs

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Taken in accordance with instructions on the label and an appropriate diet and exercise regimen, GLP-1s are effective at lowering a persons weight

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This happens because the stomach muscles dont work properly and efficiently

They found that for FDA approved GLP-1s for weight loss, liraglutide (Saxenda) and semaglutide (Wegovy), the percent of side effects reported was as follows: Nausea: 42.2% Diarrhea: 21.9% Vomiting: also 21.9% Constipation: 8.4% They report that although the incidence of side effects were similar among medications, semaglutide had the greatest risk of nausea, diarrhea, and vomiting, whereas liraglutide had the greatest risk of upper abdominal pain