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Clear headline finding from human trials Systematic reviews and metaanalyses of randomized human trials through 2024 report a modest average effect: pooled data show mean body weight reductions around 1.1 kilograms and fatmass reductions near 1.15 kilograms compared with placebo
In people with autoimmune diseases such as lupus, rheumatoid arthritis, or Hashimotos thyroiditis, this regulation becomes dysfunctional
Most effective consumer topicals fall between 1 and 2%
But there are root causes
10.1021/acs.chemrev.7b00205 Chem
If the health-care system fails to meet the needs of patients, people will look for their own solutions
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