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Unlike mTORC1, in mTORC2, rictor and msin1 block the binding of the FKBP12-rapamycin complex to the FRB domain of mTORC2, thus revealing the potential mechanism underlying the insensitivity of mTORC2 to rapamycin (Fig
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PMID: 85 Matey-HernandezMLWilliamsFMKPotterTValdesAMSpectorTDMenniC
Date: October 18, 2015 Event: Annual Meeting of the Society for Neuroscience Location: Chicago Ee Rah Sung Timing of SCH 23390 Administration Influences Extinction of Conditioned Hyperactivity in Mice