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Rare but serious gastrointestinal complications have been reported in post-marketing surveillance, including: Acute pancreatitis : If suspected, the GLP-1 agonist should be stopped immediately and not restarted if pancreatitis is confirmed Severe gastroparesis : Rare post-marketing reports of severe delayed gastric emptying Intestinal obstruction : Very rare cases reported in post-marketing surveillance Patients should be advised to seek urgent medical help via NHS 111, A&E or 999 as appropriate if they experience severe or persistent abdominal pain, persistent vomiting, abdominal distension, inability to pass stool or gas, or bloody diarrhoea whilst taking GLP-1 agonists
Candidiasis (oropharyngeal)
One raises the underlying signal, and the other delivers a clean pulse on top of it
As mentioned, some users report an altered sense of smell
Persistent Fatigue : Ongoing tiredness or muscle weakness that doesnt improve with rest
Sita = sitagliptin, BIA = brain ischemic area
