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The biased agonism toward cAMP generation at the GLP-1 receptor avoids receptor internalization, contributing to increased insulinotropic effects with fewer gastrointestinal side effects at equivalent efficacy 1,3

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Michael Donnino introduced the term gastrointestinal beriberi (63) to describe a distinct clinical entity caused by TD in the gastrointestinal system

Meanwhile, the EDS mapping of BP@CeO x also revealed the uniform distribution of Ce element across the BP nanosheet, which could support the homogeneous decoration of CeO x on the BP surface

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