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Schoenaker, D

A deeper insight into how the diverse hallmarks of aging contribute hierarchically in different organs offers a clear foundation for combination therapies aimed at various biological pathways involved in the decline of specific tissues

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At 5 years, top-dose phentermine/topiramate was preferred 84.3% of the time and lifestyle counseling was preferred 10.7% of the time

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Ongoing trials aim to clarify: Cardiovascular safety Long-term weight durability Role in prediabetes and non-diabetic populations Comparison to semaglutide and tirzepatide Until then, we continue to emphasize current best practices: lifestyle support, personalized nutrition, advanced lipid testing, and thoughtful pharmacotherapy