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GSH biosynthesis is generally performed by two consecutive ATP-consuming reactions catalyzed by -glutamylcysteine synthetase (-GCS, GSHI) and glutathione synthetase (GS, GSHII) from three precursors in microorganisms: l-glutamate, l-cysteine, and glycine [1]

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This contributes to the absorption mechanism of oral vitamin B12, which does not depend only on intrinsic factors, but the absorption can be done through passive diffusion