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Incretin combination drug development With the increased efficacy seen with dual agonism and the opportunities for combining pharmacologies in unimolecular peptides, it is unsurprising that many other incretin combination treatments are currently in development for T2D, obesity, and other metabolic disease indications

PGN cannot form gels because the molecules are not long enough to form meaningful helical structures due to their lower Mw (Blakemore 2015 Blakemore, W