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Regulatory Approvals & Global Adoption GLP-1 receptor agonists have received approvals from several regulatory authorities

Tesamorelin for reduction of visceral fat in HIV-associated lipodystrophy

Studies do seem to prove that it may work as advertised, though oral and topical supplementation is erratic and needs consistent application

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Large trials (such as the ongoing EVOKE study) are now testing whether these drugs can directly slow cognitive decline in early Alzheimers

Preclinical studies using native GLP-1 or GLP-1RA have provided convincing evidence of its cardioprotective benefits, while clinical trials have shown positive effects on hypertension and dyslipidemia in patients with T2DM [3]