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Journal reference: Corrao S, Pollicino C, Maggio D, Torres A and Argano C (2024) Tirzepatide against obesity and insulin-resistance: pathophysiological aspects and clinical evidence

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Nat Rev Mol Cell Biol (2021) 22:26682

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Although there are some experimental skin patches where GLP-1 agonist medicines like semaglutide are used as active ingredients, these are still under trial and not yet approved for use

Injections bypass gut absorption problems and deliver a predictable dose into muscle or subcutaneous tissue