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Research shows that approximately two-thirds of patients regain weight when they stop GLP-1 receptor agonists, and even a 25 to 30 day gap can trigger some weight regain if dietary habits are not maintained

(These drugs are also known as Ozempic and Mounjaro when people take the same medications for diabetes.) And the amount of weight people lost with retatrutide matches or exceeds the amount of weight people lose when they have bariatric weight-loss surgery

Nausea, abdominal pain, and heartburn are common side effects that can interrupt sleep, with heartburn often worse at night

Second, it was conducted in postmenopausal women with already-reduced bone density - not in women actively undergoing rapid weight loss or GLP-1 therapy

Recent research has shown that DOX-induced ferroptosis in cardiomyocytes is reliant on GPX4, specifically GPX4 in mitochondria