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Surgeries that affect the stomach where intrinsic factor is made, or the ileum (the last portion of the small intestine) where vitamin B12 is absorbed, can increase the risk of a deficiency

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It is not a major substrate for CYP450 enzymes

The tumor suppressor gene phosphatase and tensin homolog deleted on chromosome 10 ( PTEN ) inactivation by oxidation is perhaps the finest illustration related with cancer growth [26, 27]

Vitamin B12 Deficiencies are often seen in conditions such as

GSH is a crucial intracellular small-molecule reducing agent that effectively removes ROS and plays a vital role in the redox homeostasis of tumor cells ( Gln regulates the redox state of cancer cells and influences mitochondrial ROS production