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On the other hand, VX-497 was less toxic than 354 and the truncated USP14 interactor 352 (Fig

In particular, G6PD is essential in preserving the integrity of erythrocytes because, lacking mitochondria, they have no other NADPH-generating enzymes to protect against oxidative stress 2

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Ubiquitin-dependent degradation of certain protein substrates in vitro requires the molecular chaperone HSC70