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Accordingly, mediation analysis of LEADER and SUSTAIN-6 suggested that HbA1c and SBP lowering might partially mediate the GLP-1RA renal benefits

doi: 10.1152/ajpcell.00188.2022 48

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They were injected hypodermically (i.h.) with 20 mg kg 1 MPTP (Sigma-Aldrich, M0896) dissolved in saline once a day for 5 consecutive days and then left alone for 3 days

And when you start doing head banging, you go for a year or two on a clinical trial and then its negative, you say, What are we doing here? So I kind of thought that there was other opportunities and the excitement going on, for example, in cancer, in immune diseases, system diseases, many other things that just seem to be more stimulating that could use the new tools that we were starting to see

Part 1: diagnostics - update 2019