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In addition, HMSeBA treatment significantly increased the expression of glutathione peroxidase 4 (GPX4) and SELS, while decreased ROS level and the expression of ER stress markers induced by hydrogen peroxide (H 2 O 2 ) in IPEC-J2 cells

Illustratively, in rats with esophagogastric anastomosis [115], at the site of anastomosis and along with anastomosis healing, BPC 157 therapy promptly realized a sphincter-like function and efficiently substituted the original sphincter function