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Hypoglycaemic episodes were defined as confirmed when they were either severe according to the American Diabetes Association definition, i.e
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The FDA-approved dose of 1.75 mg was chosen partly to balance efficacy against the nausea rate seen at higher doses in early trials
However, he added that, in his opinion, a study comparing semaglutide with other meds to treat diabetes and heart failure would be helpful. Wright noted that [i]t now seems likely that cornerstone therapy for type 2 diabetic patients with obesity should be coadministration of an SGLT2 inhibitor and a GLP-1 receptor agonist, instead of the historic and perhaps now somewhat obsolete treatment with metformin and insulin. Whether their optimism is justified remains to be seen, but this study suggests that semaglutide could be an effective treatment for heart failure associated with diabetes.
Dizziness or Headache: If severe, stop use and consult a healthcare professional
