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Biochem Med

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However, the patient experienced weight gain during this period as an adverse reaction (Figure 2, Table 2, and Appendices C-M)

The shorter estimate (21 days) provides safety margin

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The proposed mechanism centers on modulation of the nitric oxide system: BPC-157 counteracts L-NAME-induced eNOS blockade in rat models and supports vascular sprouting through VEGFR2 internalization (Hsieh et al., J Mol Med , 2017)