Abbreviations Ctrl: Control EASE: Expression analysis systematic explorer FDR: False discovery rate GSH: Glutathione GSSG: Glutathione disulfide KO: Knockout MAPK: Mitogen-activated protein kinase MT: Metallothionein PCA: Principal component analysis PHH: Primary human hepatocytes RLU: Relative light units ROS: Reactive oxygen species WD: Wilsons disease References Sandahl TD, Laursen TL, Munk DE, Vilstrup H, Weiss KH, Ott P (2020) The prevalence of wilsons disease: an update
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In other human trials, oral GSH supplements could boost cytotoxicity against K562 cells (36, 37), and low glutathione in blood tracked with low cytotoxicity in autistic patients (38), however, these studies differ from ours in that whole PBMCs were used for the cytotoxicity assays instead of isolated NK cells
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