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If you experience elevated liver enzymes, explore the timeline and discuss possibilities with your healthcare provider

This suggests the evidence, while encouraging, is mixed

Brahmer JR, et al

This contrasts with controlled animal model findings, which may not accurately reflect real-world complexities

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The combined effect creates a metabolic state where appetite is significantly reduced, gastric emptying is slowed (meaning food stays in the stomach longer and meals feel more satisfying), insulin dynamics are optimized for fat mobilization rather than fat storage, and resting energy expenditure is elevated through glucagon-mediated thermogenesis