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If you experience any severe or persistent side effects, discontinue use and consult your healthcare provider immediately

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doi: 10.1152/ajprenal.00351.2019 23 LiX.ZouY.XingJ.FuY

In this review, we have discussed the potential mechanisms of renal tubular injury in DKD, including hyperglycemia, lipid accumulation, oxidative stress, hypoxia, RAAS, ER stress, inflammation, EMT and programmed cell death