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In laboratory settings, NAC has been observed to contribute to glutathione levels by providing cysteine, one of three amino acids necessary for glutathione formation

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Mechanistically, it could be because PI3K activates AKT via downstream molecules, and AKT activates mTOR by phosphorylation

Another relevant study from the American Journal of Clinical Nutrition examined obese adults undergoing caloric restriction (800 kcal/day) for 12 weeks

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