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Notes: Intended as a beauty supplement, not a substitute for a balanced diet

Additionally, NAD is a substrate for ADP-ribosyltransferases, which catalyze ADP-ribose transfer reactions, converting NAD into nicotinamide and ADP-ribosylated products (1315)

A review of systems revealed dark undereye circles, snoring, hair loss, hoarse voice, joint pain, brain fog, dry skin, and eczema

What to do with results: If markers improved, you have evidence the protocol worked

Other treatments that might be more effective include: Laser Therapy: Brightening and collagen-inducing beams of the laser also work around the eyes and can erase unwanted pigmentation to eliminate dark circles

Across the 39 platforms we reviewed, the average Trustpilot rating was ~4.0/5.0 stars, but the range was dramatic