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Binding an epitope spanning three domains, proximal only in the prefusion state, the nanobody keeps wild-type HSV-2 gB in this conformation and enabled its native prefusion structure to be determined

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Ketone Bodies During periods of fasting and some other physiological conditions, water-soluble molecules that may contain a ketone group, such as acetoacetate, hydroxybutyrate, and the spontaneous breakdown product of acetoacetate, acetone, are produced from acetyl-coA by the liver after oxidation of fatty acids

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