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The most commonly reported side effects during the first month are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, consistent with other GLP-1-containing therapies

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Anecdotally, health systems have closed hospital-based metabolic bariatric surgery programs due to decreased demand, but empirical data on the association of increased prescribing of GLP-1 [receptor agonists] with use of metabolic bariatric surgery is unavailable, to our knowledge, Kevin Lin, BA, from Harvard Medical School, and colleagues wrote in JAMA Network Open

This means that it has no recognized medical use and is considered to have a high potential for abuse

Finally, inhibition of GGT activity deprives tumours of cysteine and slows their growth