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Focus on a balanced diet built around lean protein, vegetables, and fibre-rich complex carbohydrates, while minimising known reflux triggers like fatty foods, alcohol, caffeine, and spicy foods
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Bioavailable cysteine: * Supplies the limiting substrate for glutathione synthesis * Supports the transsulfuration pathway * Assists in detoxification of homocysteine * Improves insulin sensitivity (important in cardiovascular risk) * Supports ATP production in cardiac tissue In individuals with APOE 3/4 or 4/4, the goal is not just to treat a gene
Additionally, it is worth noting that the specificity of metabolomic profiles need to be investigated in disease controls, and the heterogenous nature of ME/CFS may mean different ME/CFS subtypes could have different metabolomic profiles, which requires further investigation for diagnostic application
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