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Chronic uninterrupted use beyond 4 weeks lacks safety data

Patients should also report persistent nodules, hard lumps, or skin changes at injection sites to their healthcare provider

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According to FDA prescribing information, the most common side effects include nausea, vomiting, diarrhea, and constipation, particularly during dose escalation

GLP-1 medications are designed to copy or boost that effect

Figure 16: Painting of Professor John C Brown (19382016) by his grandson, Matthew T Kieffer, credit: Kieffer